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No.09-018
Detection of actin polymerization using split luciferase

Why measure actin polymerization in live cells? Actin polymerization concerns wide variety of cellular events. Real time detection of actin polymerization in live cell helps to elucidate the mechanism of these events.
We invented a split luciferase probe to measure actin polymerization in live cell and animal. This probe permits long-term quantitative measurement of F-actin that has been difficult.

Comparison between our probe and conventional methods for F-actin detection
Uses & Applications
Measuring the dynamic state of CREB or actin in real time
Application/Publication No.
WO/2010/018840(18.02.2010)


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