New Pt(II) Compounds with Less Nephrotoxicity
In Euro carboplatin is frequently used, while cisplatin is not frequently used because of its nephrotoxicity. Water soluble Pt anticancer drug (carboplatin etc) are frequently used.
Novelty of Pt compounds developed
- Proteasome / histone deacetylase inhibitor (New mode)
- Effective resistant cell
- No similarity (cancer panel)
- New mode of DNA binding
- Excellent adsorption to hydroxyapatite (bone) -> application for bone cancer, DDS by apatite
- Uses & Applications
- Cancer Therapy Product
- Application/Publication No.
- Patent Filed
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